Oddway International

Eltrombopag 50 mg and Pregnancy: What Are the Risks?

Eltrombopag 50 mg is a medication used to treat low platelet counts in individuals with conditions like primary immune thrombocytopenia (ITP) or thrombocytopenia associated with hepatitis C virus (HCV) infections. 

For women who require this medication, understanding the potential risks during pregnancy is crucial. 

What is Eltrombopag and What is it Used For?

Eltrombopag 50 mg is a prescription medication that stimulates the bone marrow to produce more platelets, which help in blood clotting. It is commonly used to treat:

  • Chronic immune thrombocytopenia (ITP) 
  • Thrombocytopenia in patients with chronic hepatitis C
  • Severe aplastic anemia (SAA) 


Understanding the Risks

Eltrombopag should be used during pregnancy only in the standard doses of 50 mg & 25 mg, if the potential benefit justifies the potential risk to the fetus. There is limited data available to fully assess the risks. Important points to consider:

  • FDA Pregnancy Category: Eltrombopag has been assigned to pregnancy risk category C, meaning it should be administered carefully during pregnancy, only when benefits outweigh potential risks.


  • Animal Studies: Animal studies have shown embryolethality and reduced fetal weights at maternally toxic doses.


  • Human Data: There is insufficient data to assess drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes in humans.


  • Potential Risks: Possible risks include preeclampsia and fetal growth restriction.

It's essential to discuss these risks thoroughly with a healthcare provider.

Important Considerations for Pregnant Women

  • Contraception: Sexually active females should use effective contraception during treatment with Eltrombopag and for at least 7 days after stopping the drug.


  • Monitoring: Regular monitoring by a doctor is essential to ensure the medication is working properly and to check for potential liver problems.


  • Symptoms to Watch For: Contact your doctor immediately if you experience symptoms such as nausea, vomiting, dark urine, light-colored stools, or right upper stomach pain.


Alternatives and Management

Refractory ITP in pregnancy is complex, and Eltrombopag is often considered a second-line agent. A multidisciplinary approach to managing ITP during pregnancy is crucial and treatment costs vary based on the Eltrombopag price in different markets.

 

Purchasing Eltrombopag 50 mg Online

Oddway International supplies Eltrombopag 50 mg under various brands, including:

  • Eltromag (Cipla)
  • Trombonat (Natco Pharma)
  • Rompag (Hetero Healthcare)
  • Eltrog (Glenmark Pharma)

Oddway International provides both wholesale and single orders of Eltrombopag tablets, shipping to locations within India and worldwide. 

Disclaimer: Consult a healthcare professional before purchasing any medication online.